新型免疫调节因子和肿瘤研究组

http://sysadmin.xun-ao.com/d/file/2016-12-01/9adce3a0ad11ec98390d05415a7af32f.png 负责人:沈南研究员 

沈南,男,上海交通大学/医学院-仁济医院,教授、主任医师。

国家973首席科学家,国家杰出青年基金获得者。担任上海市风湿病学研究所所长,中国科学院上海生命科学研究院健康科学研究所分子风湿病学研究组组长。先后在美国UCLA大学风湿病学中心, 荷兰阿姆斯特丹大学医学中心学习进修,并获得阿姆斯特丹大学博士学位。在多个国际重要的学术团体任职,包括美国风湿病学会策划委员会委员,亚太地区风湿病学联盟科学顾问委员会委员等,并在国际上多本重要的学术期刊上担任编委和副主编。获得国家科学技术进步奖二等奖,中国高等学校科技进步奖一等奖等省部级奖项6项,并于2009年获得上海市领军人才和新世纪百千万人才工程国家级人选。长期从事系统性红斑狼疮的发病机理及靶向治疗研究,近年来通过功能基因组学、细胞及分子免疫学等多种策略在SLE关键性致病通路的研究中取得显著进展。在Nature MedicinePlos geneticsBloodJ ImmunolPNAS等杂志上发表SCI收录论文60余篇,ISI引用1418次。

 

主要研究方向:

1.干扰素通路与免疫调节;

2.非编码RNA与免疫反应;

3.个体化免疫与肿瘤.

 

Section of Novel Immune Regulator and Tumor

 Prof. Nan Shen MD, PhD

 

Dr. Nan Shen received his medical degree from Shanghai Second Medical University and PhD degree from University of Amsterdam.  Dr. Shen is a Professor of Medicine and Director of Shanghai Institute of Rheumatology, Ren Ji Hospital Shanghai Jiao Tong University, School of Medicine , as well as a Principal Investigator, Head of Lab of Molecular Rheumatology at Health Science Institute, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. He also hold an appointment as Adjunct Professor at Center for Autoimmune Genomics and Etiology ,Cincinnati Children's Hospital Medical Center , University of Cincinnati. His research mainly focuses on the molecular dissection of the disease pathways in systemic autoimmune diseases by functional genomics approach and the development of novel biomarkers and therapeutic targets in the management of systemic lupus erythematosus. He has published over 90 papers in peer-reviewed journals and has also been invited to deliver oral presentations at many high-profile international conferences. His research contributions has been recognized with several prestigious awards.

 

Research interests

1Interferon pathway and immune regulation;

2Non-coding RNA and immune response;

Personalized immunology and tumor progession.

 

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